Shun Chen Selected Research

Plague (Bubonic Plague)

7/2022	Differential expression profile and in-silico functional analysis of long noncoding RNA and mRNA in duck embryo fibroblasts infected with duck plague virus.
6/2022	The protein encoded by the duck plague virus UL14 gene regulates virion morphogenesis and affects viral replication.
3/2022	Duck plague virus UL41 protein inhibits RIG-I/MDA5-mediated duck IFN-β production via mRNA degradation activity.
1/2022	Evaluation of the Safety and Immunogenicity of Duck-Plague Virus gE Mutants.
6/2021	The intracellular domain of duck plague virus glycoprotein E affects UL11 protein incorporation into viral particles.
5/2021	SC75741 antagonizes vesicular stomatitis virus, duck Tembusu virus, and duck plague virus infection in duck cells through promoting innate immune responses.
1/2021	Duck Plague Virus pUL48 Protein Activates the Immediate-Early Gene to Initiate the Transcription of the Virus Gene.
1/2021	UL11 Protein Is a Key Participant of the Duck Plague Virus in Its Life Cycle.
12/2020	Research Note: Duck plague virus glycoprotein I influences cell-cell spread and final envelope acquisition.
1/2020	Binding of Duck Tembusu Virus Nonstructural Protein 2A to Duck STING Disrupts Induction of Its Signal Transduction Cascade To Inhibit Beta Interferon Induction.

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Shun Chen Research Topics

Disease

64	Infections 07/2022 - 09/2008
26	Enteritis 01/2021 - 04/2008
25	Virus Diseases (Viral Diseases) 05/2022 - 11/2014
24	Plague (Bubonic Plague) 07/2022 - 04/2014
7	Bites and Stings (Sting) 03/2022 - 01/2018
7	Neoplasms (Cancer) 12/2021 - 04/2014
6	Flavivirus Infections 01/2021 - 01/2017
5	Influenza in Birds (Avian Flu) 01/2017 - 05/2014
4	Melanoma (Melanoma, Malignant) 03/2022 - 09/2013
4	Ischemia 10/2011 - 02/2009
3	Viremia 05/2022 - 05/2015
3	Porcine Reproductive and Respiratory Syndrome (PRRS) 11/2021 - 08/2015
3	Herpes Simplex 01/2020 - 11/2015
3	Burns 01/2017 - 04/2004
2	Inflammation (Inflammations) 01/2022 - 01/2022
2	Coinfection 08/2021 - 01/2018
2	Sepsis (Septicemia) 01/2017 - 05/2014
2	Necrosis 09/2008 - 04/2008
1	Atherosclerosis 03/2022
1	Cholera 03/2022
1	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/2022
1	Body Weight (Weight, Body) 01/2022
1	Neoplasm Metastasis (Metastasis) 12/2021
1	Lymphatic Metastasis 12/2021
1	Vesicular Stomatitis 05/2021
1	Persistent Infection 01/2021
1	Pulmonary Arterial Hypertension 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 01/2021
1	Hypoxia (Hypoxemia) 01/2021
1	Chronic Hepatitis (Chronic Active Hepatitis) 01/2021

Drug/Important Bio-Agent (IBA)

39	Proteins (Proteins, Gene)FDA Link 06/2022 - 04/2013
25	Antiviral Agents (Antivirals)IBA 05/2022 - 01/2015
14	VaccinesIBA 05/2022 - 04/2014
13	Messenger RNA (mRNA)IBA 07/2022 - 11/2012
12	RNA (Ribonucleic Acid)IBA 07/2022 - 01/2014
12	InterferonsIBA 03/2022 - 11/2014
10	butyl phosphorotrithioate (DEF)IBA 07/2022 - 04/2008
8	CytokinesIBA 11/2021 - 01/2015
7	Glycoproteins (Glycoprotein)IBA 06/2021 - 10/2013
6	Interferon Type IIBA 11/2020 - 01/2016
4	DNA (Deoxyribonucleic Acid)IBA 07/2022 - 01/2018
4	Viral ProteinsIBA 01/2022 - 01/2020
4	Peptide Hydrolases (Proteases)FDA Link 01/2022 - 11/2017
4	MicroRNAs (MicroRNA)IBA 01/2020 - 05/2012
3	Biological ProductsIBA 05/2022 - 01/2017
3	AntibodiesIBA 05/2022 - 05/2015
3	Phosphotransferases (Kinase)IBA 03/2022 - 01/2020
3	Interleukin-6 (Interleukin 6)IBA 01/2022 - 10/2015
3	Poly I-CIBA 01/2022 - 01/2016
3	Staphylococcal Protein A (Protein A)IBA 01/2021 - 01/2017
3	Small Interfering RNA (siRNA)IBA 01/2021 - 04/2014
3	Capsid Proteins (Capsid Protein)IBA 08/2019 - 08/2015
3	DNA VaccinesIBA 01/2018 - 07/2012
3	Pattern Recognition ReceptorsIBA 01/2017 - 08/2015
3	ODN2006IBA 01/2017 - 01/2016
2	Long Noncoding RNAIBA 07/2022 - 12/2021
2	Caspase 3 (Caspase-3)IBA 07/2022 - 01/2022
2	Polysaccharides (Glycans)IBA 03/2022 - 04/2020
2	Attenuated VaccinesIBA 03/2022 - 01/2018
2	CaspasesIBA 01/2022 - 01/2019
2	GTP Phosphohydrolases (GTPases)IBA 12/2021 - 08/2016
2	Amino Acids FDA Link 01/2021 - 01/2018
2	Nuclear Localization Signals (Nuclear Localization Signal)IBA 01/2021 - 01/2016
2	Complementary DNA (cDNA)IBA 01/2021 - 01/2018
2	LuciferasesIBA 01/2021 - 04/2014
2	Suppressor of Cytokine Signaling ProteinsIBA 01/2021 - 01/2020
2	Etoposide (VP 16)FDA LinkGeneric 01/2020 - 01/2016
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2020 - 01/2020
2	Cystatin CIBA 01/2020 - 11/2019
2	Interferon Regulatory Factor-7 (Interferon Regulatory Factor 7)IBA 01/2020 - 01/2019
2	Tretinoin (Retinoic Acid)FDA LinkGeneric 01/2020 - 01/2016
2	Therapeutic UsesIBA 08/2019 - 04/2004
2	OligodeoxyribonucleotidesIBA 01/2019 - 03/2016
2	NucleotidesIBA 12/2017 - 05/2012
2	ParaffinIBA 08/2009 - 04/2009
2	paraform (paraformaldehyde)IBA 08/2009 - 04/2009
2	FITC-annexin A5IBA 09/2008 - 04/2008
1	Matrix Metalloproteinases (MMPs)IBA 07/2022
1	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2022
1	Apoptosis Regulatory ProteinsIBA 07/2022
1	Death Domain ReceptorsIBA 07/2022
1	Cytochromes c (Cytochrome c)IBA 07/2022
1	Interferon Regulatory FactorsIBA 03/2022
1	Granzymes (Granzyme)IBA 01/2022
1	Zinc Oxide FDA Link 01/2022
1	6-methyladenineIBA 01/2022
1	AntioxidantsIBA 01/2022
1	Immunoglobulin A (IgA)IBA 01/2022
1	ORALIT (ORS)IBA 12/2021
1	vasectrin I (VS I)IBA 12/2021
1	Interleukin-4 (Interleukin 4)IBA 11/2021
1	Interleukin-2 (IL2)IBA 11/2021
1	SC75741IBA 05/2021
1	Adenosine Triphosphate (ATP)IBA 01/2021
1	Interleukin-7 (Interleukin 7)IBA 01/2021
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2021
1	LipidsIBA 01/2021
1	Interleukin-7 Receptors (Interleukin 7 Receptor)IBA 01/2021
1	Protein Kinases (Protein Kinase)IBA 01/2021

Therapy/Procedure

7	Therapeutics 09/2020 - 12/2010